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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15385 | Glibornuride | Potassium Channel | |
Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent. | |||
T29457L | 5-Hydroxydecanoate sodium | Potassium Channel | |
5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker with IC50 of about 30 μM. 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase with antioxidant p... | |||
T2404 | Vonoprazan fumarate | TAK-438 | ATPase |
Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase. | |||
T17030 | Tegoprazan | ATPase , Proton pump | |
Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5... | |||
T2024 | A-803467 | A 803467,A803467 | Sodium Channel |
A-803467 is a selective NaV1.8 channel blocker. | |||
T70801 | ZM-181037 | ||
ZM-181037 is an ATP-sensitive potassium channel-blocker and a eukalemic diuretic. | |||
T28977 | Tilisolol HCl | Tilisolol, trade name Selecal,N 696,N-696,N696 | |
Tilisolol is a nonselective blocker of beta-adrenergic. Tilisolol hydrochloride dilates coronary arteries through an ATP-sensitive K(+)-channel opening mechanism in dogs. | |||
T15386 | Glisoxepide | Others | |
Glisoxepide is a sulphonamide derivative and is an orally available nonselective K(ATP) channel blocker. It has antihyperglycemic activity and cardiovascular regulation effect. | |||
T11243 | Ethyl tosylcarbamate | Others | |
Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Ethyl tosylcarbamate is an intermediate in the synthesis of Gliclazide (G409877). | |||
T63330 | Clamikalant sodium | ||
Clamikalant sodium is a non-selective, ATP-sensitive potassium (KATP) channel blocker that can be used to study cardiac arrhythmias. | |||
T41204 | TAT-Gap19(I130A) | TAT-Gap19(I130A) | |
TAT-Gap19(I130A) is a control peptide for TAT-Gap19, a Cx43 hemichannel blocker. TAT-Gap19(I130A) consists of TAT-GAP19 with a I130A amino acid residue change at a key residue for GAP19 activity. In C6 glioma cells expre... | |||
T11731L | JTV-519 Formate | JTV-519 Formate (145903-06-6 Free base) | Others , Calcium Channel |
JTV-519 Formate is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA). JTV-519 Formate is also a partial agonist of ryanodine receptors in striated muscle. JTV-519 Formate exhibits antiarrh... |